Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum.

Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite utilized as a redox cofactor and enzyme substrate in numerous cellular processes. Elevated NAD+ levels have been observed in red blood cells infected with the malaria parasite Plasmodium falciparum, but little is known regarding how...

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Bibliographic Details
Main Authors: Jessica K O'Hara, Lewis J Kerwin, Simon A Cobbold, Jonathan Tai, Thomas A Bedell, Paul J Reider, Manuel Llinás
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3991606?pdf=render