Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy

BACKGROUND: Pulmonary arterial hypertension (PAH) remains a progressive disease despite improvement when using one of three medication classes: prostanoids, endothelin receptor antagonists or phosphodiesterase-5 inhibitors. Combination therapy has been proposed for patients with unsatisfactory respo...

Full description

Bibliographic Details
Main Authors: Nancy R Porhownik, Hassan Al-Sharif, Zoheir Bshouty
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2008/897102