Hippocampal CA3 transcriptional modules associated with granule cell alterations and cognitive impairment in refractory mesial temporal lobe epilepsy patients

Hippocampal CA3 transcriptional modules associated with granule cell alterations and cognitive impairment in refractory mesial temporal lobe epilepsy patients

Abstract In about a third of the patients with epilepsy the seizures are not drug-controlled. The current limitation of the antiepileptic drug therapy derives from an insufficient understanding of epilepsy pathophysiology. In order to overcome this situation, it is necessary to consider epilepsy as...

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Bibliographic Details
Main Authors: Silvia Yumi Bando, Fernanda Bernardi Bertonha, Luciana Ramalho Pimentel-Silva, João Gabriel Mansano de Oliveira, Marco Antonio Duarte Carneiro, Mariana Hiromi Manoel Oku, Hung-Tzu Wen, Luiz Henrique Martins Castro, Carlos Alberto Moreira-Filho
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89802-3

Internet

https://doi.org/10.1038/s41598-021-89802-3

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