Mitigation of cholestasis-associated hepatic and renal injury by edaravone treatment: Evaluation of its effects on oxidative stress and mitochondrial function

Mitigation of cholestasis-associated hepatic and renal injury by edaravone treatment: Evaluation of its effects on oxidative stress and mitochondrial function

Background and aim: The liver is the primary organ affected by cholestasis, and complications such as renal injury, renal failure, and the need for renal transplantation are associated with cholestatic liver disease. There is substantial evidence indicating that reactive oxygen species (ROS) and mit...

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Bibliographic Details
Main Authors: Mohammad Mehdi Ommati, Hanie Attari, Asma Siavashpour, Marzieh Shafaghat, Negar Azarpira, Hasti Ghaffari, Leila Moezi, Reza Heidari
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-09-01
Series:Liver Research
Subjects:
Bile acids
Cholestasis
Cirrhosis
Nephropathy
Oxidative stress
Renal failure
Online Access:http://www.sciencedirect.com/science/article/pii/S254256842030057X

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http://www.sciencedirect.com/science/article/pii/S254256842030057X

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