Modulation of tumor necrosis factor by microbial pathogens.

In response to invasion by microbial pathogens, host defense mechanisms get activated by both the innate and adaptive arms of the immune responses. TNF (tumor necrosis factor) is a potent proinflammatory cytokine expressed by activated macrophages and lymphocytes that induces diverse cellular respon...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-02-01
Series:PLoS Pathogens
Online Access:http://dx.doi.org/10.1371/journal.ppat.0020004