Evaluation of imatinib mesylate (Gleevec) on KAI1/CD82 gene expression in breast cancer MCF-7 cells using quantitative real-time PCR

Evaluation of imatinib mesylate (Gleevec) on KAI1/CD82 gene expression in breast cancer MCF-7 cells using quantitative real-time PCR

Objective: To evaluate the effect of imatinib mesylate on cell viability, anti cancer effect through modulation of KAI1/CD82 gene expression in breast cancer MCF-7 cell line. Methods: The effects of imatinib mesylate on cell viability in MCF-7 cell line were assessed using MTT assay and IC50 value w...

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Bibliographic Details
Main Authors: Seyed Ataollah Sadat Shandiz, Marjan Khosravani, Sepideh Mohammadi, Hassan Noorbazargan, Amir Mirzaie, Davoud Nouri Inanlou, Mojgan Dalirsaber Jalali, Hamidreza Jouzaghkar, Fahimeh Baghbani-Arani, Behta Keshavarz-Pakseresht
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-02-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Imatinib mesylate
KAI1/CD82
Metastasis
Breast cancer
Real-time PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169115002567

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http://www.sciencedirect.com/science/article/pii/S2221169115002567

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