Food anticipatory activity on a calorie-restricted diet is independent of Sirt1.

A number of studies have demonstrated that the Sirtuin family member, Sirt1, is a key integrator of growth, metabolism, and lifespan. Sirt1 directly interacts with and deacetylates key regulators of the circadian clock, positioning it to be an important link between feeding and circadian rhythms. In...

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Bibliographic Details
Main Authors: Dina R Assali, Cynthia T Hsu, Keith M Gunapala, Antonio Aguayo, Michael McBurney, Andrew D Steele
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6016907?pdf=render