TNF-alpha neutralizing antibody blocks thermal sensitivity induced by compound 48/80-provoked mast cell degranulation [v1; ref status: indexed, http://f1000r.es/1mq]

TNF-alpha neutralizing antibody blocks thermal sensitivity induced by compound 48/80-provoked mast cell degranulation [v1; ref status: indexed, http://f1000r.es/1mq]

Background:  Neuro-inflammatory circuits in the tissue regulate the complex pathophysiology of pain.  Protective nociceptive pain serves as an early warning system against noxious environmental stimuli.  Tissue-resident mast cells orchestrate the increased thermal sensitivity following injection of...

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Bibliographic Details
Main Authors: Devavani Chatterjea, Luisa Paredes, Tijana Martinov, Evelyn Balsells, Juliann Allen, Akilah Sykes, Alyssa Ashbaugh
Format: Article
Language:English
Published: F1000 Research Ltd 2013-08-01
Series:F1000Research
Subjects:
Allergy & Hypersensitivity
Leukocyte Signaling & Gene Expression
Online Access:http://f1000research.com/articles/2-178/v1

Internet

http://f1000research.com/articles/2-178/v1

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