Introduction of Exogenous HSV-TK Suicide Gene Increases Safety of Keratinocyte-Derived Induced Pluripotent Stem Cells by Providing Genetic “Emergency Exit” Switch

Introduction of Exogenous HSV-TK Suicide Gene Increases Safety of Keratinocyte-Derived Induced Pluripotent Stem Cells by Providing Genetic “Emergency Exit” Switch

Since their invention in 2006, induced Pluripotent Stem (iPS) cells remain a great promise for regenerative medicine circumventing the ethical issues linked to Embryonic Stem (ES) cell research. iPS cells can be generated in a patient-specific manner as an unlimited source of various cell types for...

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Bibliographic Details
Main Authors: Maciej Sułkowski, Paweł Konieczny, Paula Chlebanowska, Marcin Majka
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
induced Pluripotent Stem (iPS)
suicide gene therapy
genetic safeguarding
Online Access:http://www.mdpi.com/1422-0067/19/1/197

Internet

http://www.mdpi.com/1422-0067/19/1/197

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