Clinical Diversity in Focal Congenital Hyperinsulinism in Infancy Correlates With Histological Heterogeneity of Islet Cell Lesions

Clinical Diversity in Focal Congenital Hyperinsulinism in Infancy Correlates With Histological Heterogeneity of Islet Cell Lesions

Background: Congenital Hyperinsulinism (CHI) is an important cause of severe and persistent hypoglycaemia in infancy and childhood. The focal form (CHI-F) of CHI can be potentially cured by pancreatic lesionectomy. While diagnostic characteristics of CHI-F pancreatic histopathology are well-recogniz...

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Main Authors: Ross J. Craigie, Maria Salomon-Estebanez, Daphne Yau, Bing Han, Walaa Mal, Melanie Newbould, Edmund Cheesman, Stefania Bitetti, Zainab Mohamed, Rakesh Sajjan, Raja Padidela, Mars Skae, Sarah Flanagan, Sian Ellard, Karen E. Cosgrove, Indraneel Banerjee, Mark J. Dunne
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Endocrinology
Subjects:
congenital hyperinsulinism
insulin
hypoglycaemia
islet
positron emission tomography
focal
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00619/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00619/full

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