Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans
The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss-of-function mutations of stau-1 significantly sup...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2016-05-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.116.027300 |