Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans

The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss-of-function mutations of stau-1 significantly sup...

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Bibliographic Details
Main Authors: Zhiji Ren, Isana Veksler-Lublinsky, David Morrissey, Victor Ambros
Format: Article
Language:English
Published: Oxford University Press 2016-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.027300