Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS

Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS

Abstract Liquid droplets of aggregation-prone proteins, which become hydrogels or form amyloid fibrils, are a potential target for drug discovery. In this study, we proposed an experiment-guided protocol for characterizing the design grammar of peptides that can regulate droplet formation and aggreg...

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Bibliographic Details
Main Authors: Kiyoto Kamagata, Rika Chiba, Ichiro Kawahata, Nanako Iwaki, Saori Kanbayashi, Kana Maeda, Hiroto Takahashi, Atsushi Hirano, Koji Fukunaga, Keisuke Ikeda, Tomoshi Kameda
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86098-1

Internet

https://doi.org/10.1038/s41598-021-86098-1

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