Genetic Variations in the Transforming Growth Factor-β1 Pathway May Improve Predictive Power for Overall Survival in Non-small Cell Lung Cancer

Genetic Variations in the Transforming Growth Factor-β1 Pathway May Improve Predictive Power for Overall Survival in Non-small Cell Lung Cancer

Purpose: Transforming growth factor-β1 (TGF-β1), a known immune suppressor, plays an important role in tumor progression and overall survival (OS) in many types of cancers. We hypothesized that genetic variations of single nucleotide polymorphisms (SNPs) in the TGF-β1 pathway can predict survival in...

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Bibliographic Details
Main Authors: Hong Zhang, Weili Wang, Wenhu Pi, Nan Bi, Colleen DesRosiers, Fengchong Kong, Monica Cheng, Li Yang, Tim Lautenschlaeger, Shruti Jolly, Jianyue Jin, Feng-Ming (Spring) Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
machine learning
single nuclear polymorphism
overall survival
non-small cell lung cancer
TGF-β1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.599719/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.599719/full

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