Characterization of Staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1

Characterization of Staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1

The human immunodeficiency virus type 1 (HIV-1) unspliced, 9kb genomic RNA (vRNA) is exported from the nucleus for the synthesis of viral structural proteins and enzymes (Gag and Gag/Pol) and is then transported to sites of virus assembly where it is packaged into progeny virions. vRNA co-exists in...

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Bibliographic Details
Main Authors: Miroslav P. Milev, Mukunthan eRavichandran, Morgan F. Khan, David C. Schriemer, Andrew J. Mouland
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Microbiology
Subjects:
HIV-1
Mass Spectrometry
Gag
virus-host interactions
genomic RNA
gradient centrifugation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00367/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00367/full

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