Chaperone requirements for biosynthesis of the trypanosome variant surface glycoprotein.

Trypanosoma brucei does not respond transcriptionally to several endoplasmic reticulum (ER) stress conditions, including tunicamycin or dithiothreitol, indicating the absence of a conventional unfolded protein response. This suggests divergent mechanisms for quality control (QC) of ER protein foldin...

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Bibliographic Details
Main Authors: Mark C Field, Tatiana Sergeenko, Ya-Nan Wang, Susanne Böhm, Mark Carrington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2797082?pdf=render