Human HOX Proteins Use Diverse and Context-Dependent Motifs to Interact with TALE Class Cofactors

Summary: HOX proteins achieve numerous functions by interacting with the TALE class PBX and MEIS cofactors. In contrast to this established partnership in development and disease, how HOX proteins could interact with PBX and MEIS remains unclear. Here, we present a systematic analysis of HOX/PBX/MEI...

Full description

Bibliographic Details
Main Authors: Amélie Dard, Jonathan Reboulet, Yunlong Jia, Françoise Bleicher, Marilyne Duffraisse, Jean-Marc Vanaker, Christelle Forcet, Samir Merabet
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718302651