Activation of AMPA receptors in the suprachiasmatic nucleus phase-shifts the mouse circadian clock in vivo and in vitro.

The glutamatergic neurotransmission in the suprachiasmatic nucleus (SCN) plays a central role in the entrainment of the circadian rhythms to environmental light-dark cycles. Although the glutamatergic effect operating via NMDAR (N-methyl D-aspartate receptor) is well elucidated, much less is known a...

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Bibliographic Details
Main Authors: Yasutaka Mizoro, Yoshiaki Yamaguchi, Rena Kitazawa, Hiroyuki Yamada, Masahiro Matsuo, Jean-Michel Fustin, Masao Doi, Hitoshi Okamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20532181/?tool=EBI