Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury.

Several studies demonstrated that treatment with mesenchymal stem cells (MSCs) reduces cisplatin mortality in mice. Microvesicles (MVs) released from MSCs were previously shown to favor renal repair in non lethal toxic and ischemic acute renal injury (AKI). In the present study we investigated the e...

Full description

Bibliographic Details
Main Authors: Stefania Bruno, Cristina Grange, Federica Collino, Maria Chiara Deregibus, Vincenzo Cantaluppi, Luigi Biancone, Ciro Tetta, Giovanni Camussi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3303802?pdf=render