Lipophagy Impairment Is Associated With Disease Progression in NAFLD

Lipophagy Impairment Is Associated With Disease Progression in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in Western countries and is associated with aging and features of metabolic syndrome. Lipotoxicity and oxidative stress are consequent to dysregulation of lipid metabolism and lipid accumulation, leading to h...

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Bibliographic Details
Main Authors: Simone Carotti, Katia Aquilano, Francesca Zalfa, Sergio Ruggiero, Francesco Valentini, Maria Zingariello, Maria Francesconi, Giuseppe Perrone, Francesca Alletto, Raffaele Antonelli-Incalzi, Antonio Picardi, Sergio Morini, Daniele Lettieri-Barbato, Umberto Vespasiani-Gentilucci
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
autophagy
high-fat diet
lipolysosomes
non-alcoholic steatohepatitis
lipophagy
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00850/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00850/full

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