Microbial metabolite sensor GPR43 controls severity of experimental GVHD

Microbial metabolite sensor GPR43 controls severity of experimental GVHD

The microbial metabolite sensor GPR43 has been previously shown to be a crucial modulator of immune responses. Here the authors show GPR43 is required for controlling disease pathology severity in the context of experimental models of GVHD.

Bibliographic Details
Main Authors: Hideaki Fujiwara, Melissa D. Docampo, Mary Riwes, Daniel Peltier, Tomomi Toubai, Israel Henig, S. Julia Wu, Stephanie Kim, Austin Taylor, Stuart Brabbs, Chen Liu, Cynthia Zajac, Katherine Oravecz-Wilson, Yaping Sun, Gabriel Núñez, John E. Levine, Marcel R.M. van den Brink, James L. M. Ferrara, Pavan Reddy
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06048-w

Internet

https://doi.org/10.1038/s41467-018-06048-w

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