Serine protease MP2 activates prophenoloxidase in the melanization immune response of Drosophila melanogaster.

In arthropods, melanization plays a major role in the innate immune response to encapsulate and kill the invasive organisms. It is mediated by a serine protease cascade and is regulated by serpins. The identification of the molecular components of melanization and the regulation of those components...

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Bibliographic Details
Main Authors: Chunju An, Mingming Zhang, Yuan Chu, Zhangwu Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829845?pdf=render