Aberrant gene expression by Sertoli cells in infertile men with Sertoli cell-only syndrome.

Sertoli cell-only (SCO) syndrome is a severe form of human male infertility seemingly characterized by the lack all spermatogenic cells. However, tubules of some SCO testes contain small patches of active spermatogenesis and thus spermatogonial stem cells. We hypothesized that these stem cells canno...

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Bibliographic Details
Main Authors: Darius A Paduch, Stephanie Hilz, Andrew Grimson, Peter N Schlegel, Anne E Jedlicka, William W Wright
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216586