Therapeutic potential of targeting membrane-spanning proteoglycan SDC4 in hepatocellular carcinoma
Abstract Syndecan-4 (SDC4) functions as a major endogenous membrane-associated receptor and widely regulates cytoskeleton, cell adhesion, and cell migration in human tumorigenesis and development, which represents a charming anti-cancer therapeutic target. Here, SDC4 was identified as a direct cellu...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03780-y |