Impact of Histone H1 on the Progression of Allergic Rhinitis and Its Suppression by Neutralizing Antibody in Mice.

Nuclear antigens are known to trigger off innate and adaptive immune responses. Recent studies have found that the complex of nucleic acids and core histones that are derived from damaged cells may regulate allergic responses. However, no fundamental study has been performed concerning the role of l...

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Bibliographic Details
Main Authors: Toshiaki Nakano, Rikiya Kamei, Takashi Fujimura, Yuki Takaoka, Ayane Hori, Chia-Yun Lai, Kuei-Chen Chiang, Yayoi Shimada, Naoya Ohmori, Takeshi Goto, Kazuhisa Ono, Chao-Long Chen, Shigeru Goto, Seiji Kawamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4835108?pdf=render