Down-regulation of Regulatory T-cells in Children With Gaucher Disease Under Enzyme Replacement Therapy

Down-regulation of Regulatory T-cells in Children With Gaucher Disease Under Enzyme Replacement Therapy

Gaucher disease (GD) is one of the most important lysosomal storage disorders. T-lymphocytes perform and regulate many of the immune processes and play a major role in immune homeostasis. Studies have shown that GD causes impairment in T-lymphocyte functions, although the role and status of T-lympho...

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Main Authors: Asmaa M. Zahran MD, Khaled Saad MD, Mohamed Gamil Abo-Elela MD, Esraa M. Eloseily MD, Eman F. Gad MD, Amir M. Abo Elgheet MD, Rasha R. Mahmmoud MD, Mervat A. M. Youssef MD, Mona M. Abdelmeguid MD, Bahaa Hawary MD, Sanaa F. Darwish MD, Amira Elhoufey PhD, Khalid I. Elsayh MD
Format: Article
Language:English
Published: SAGE Publishing 2019-11-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/1076029619889685

Internet

https://doi.org/10.1177/1076029619889685

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