The hypothalamic–pituitary–gonadal axis controls muscle stem cell senescence through autophagosome clearance

The hypothalamic–pituitary–gonadal axis controls muscle stem cell senescence through autophagosome clearance

Abstract Background With organismal aging, the hypothalamic–pituitary–gonadal (HPG) activity gradually decreases, resulting in the systemic functional declines of the target tissues including skeletal muscles. Although the HPG axis plays an important role in health span, how the HPG axis systemicall...

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Bibliographic Details
Main Authors: Ji‐Hoon Kim, Inkuk Park, Hijai R. Shin, Joonwoo Rhee, Ji‐Yun Seo, Young‐Woo Jo, Kyusang Yoo, Sang‐Hyeon Hann, Jong‐Seol Kang, Jieon Park, Ye Lynne Kim, Ju‐Yeon Moon, Man Ho Choi, Young‐Yun Kong
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Aging
Muscle stem cell
Muscle regeneration
Cellular senescence
Sex steroid hormones
Autophagy
Online Access:https://doi.org/10.1002/jcsm.12653

Internet

https://doi.org/10.1002/jcsm.12653

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