Triazoloquinazolines as a new class of potent α-glucosidase inhibitors: in vitro evaluation and docking study.

Previously, we synthesized triazoloquinazolines 1-14 and characterized their structure. In this study, we aimed to evaluate the in vitro activity of the targets 1-14 as α-glucosidase inhibitors using α-glucosidase enzyme from Saccharomyces cerevisiae type 1. Among the tested compounds, triazoloquina...

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Bibliographic Details
Main Authors: Hatem A Abuelizz, El Hassane Anouar, Rohaya Ahmad, Nor Izzati Iwana Nor Azman, Mohamed Marzouk, Rashad Al-Salahi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220379