A novel PPARɣ ligand, PPZ023, overcomes radioresistance via ER stress and cell death in human non-small-cell lung cancer cells

Cancer: Reversing resistance to radiotherapy A novel small molecule drug candidate known as PPZ023 could be a powerful anti-cancer agent due to its ability to overcome the resistance of tumors to radiation therapy. Sung Hee Hong and colleagues at the Korea Institute of Radiological and Medical Scien...

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Bibliographic Details
Main Authors: Tae Woo Kim, Da-Won Hong, Chang-Mo Kang, Sung Hee Hong
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-00511-9