Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells

Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells

Abstract Background Gigantol is a bibenzyl compound derived from several medicinal orchids. This biologically active compound has been shown to have promising therapeutic potential against cancer cells, but its mechanism of action remains unclear. Methods The inhibitory effect of gigantol on Wnt/β-c...

Full description

Bibliographic Details
Main Authors: Shubin Yu, Zhongyuan Wang, Zijie Su, Jiaxing Song, Liang Zhou, Qi Sun, Shanshan Liu, Shiyue Li, Ying Li, Meina Wang, Guo-Qiang Zhang, Xue Zhang, Zhong-Jian Liu, Desheng Lu
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Gigantol
LRP6
Wnt/β-catenin signaling
Breast cancer
Anticancer activity
Online Access:http://link.springer.com/article/10.1186/s12906-018-2108-x

Internet

http://link.springer.com/article/10.1186/s12906-018-2108-x

Similar Items