Human induced pluripotent stem cells technology in treatment resistant depression: novel strategies and opportunities to unravel ketamine’s fast-acting antidepressant mechanisms

Approximately 30% of Major Depressive Disorder (MDD) patients develop treatment-resistant depression (TRD). Among the different causes that make TRD so challenging in both clinical and research contexts, major roles are played by the inadequate understanding of MDD pathophysiology and the limitation...

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Bibliographic Details
Main Authors: Matteo Marcatili, Carlo Sala, Antonios Dakanalis, Fabrizia Colmegna, Armando D’Agostino, Orsola Gambini, Bernardo Dell’Osso, Beatrice Benatti, Luciano Conti, Massimo Clerici
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Therapeutic Advances in Psychopharmacology
Online Access:https://doi.org/10.1177/2045125320968331