Cooperation between CD4+ T Cells and Humoral Immunity Is Critical for Protection against Dengue Using a DNA Vaccine Based on the NS1 Antigen.

Cooperation between CD4+ T Cells and Humoral Immunity Is Critical for Protection against Dengue Using a DNA Vaccine Based on the NS1 Antigen.

Dengue virus (DENV) is spread through most tropical and subtropical areas of the world and represents a serious public health problem. At present, the control of dengue disease is mainly hampered by the absence of antivirals or a vaccine, which results in an estimated half worldwide population at ri...

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Bibliographic Details
Main Authors: Antônio J S Gonçalves, Edson R A Oliveira, Simone M Costa, Marciano V Paes, Juliana F A Silva, Adriana S Azevedo, Marcio Mantuano-Barradas, Ana Cristina M A Nogueira, Cecília J Almeida, Ada M B Alves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4674122?pdf=render

Internet

http://europepmc.org/articles/PMC4674122?pdf=render

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