Sulfur Modifications of the Wobble U34 in tRNAs and their Intracellular Localization in Eukaryotic Cells

The wobble uridine (U34) of transfer RNAs (tRNAs) for two-box codon recognition, i.e., tRNALysUUU, tRNAGluUUC, and tRNAGlnUUG, harbor a sulfur- (thio-) and a methyl-derivative structure at the second and fifth positions of U34, respectively. Both modifications are necessary to construct the proper a...

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Bibliographic Details
Main Authors: Yumi Nakai, Masato Nakai, Takato Yano
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/7/1/17