Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice

Abstract Background Spermatogonial stem cell transplantation (SSCT) could become a fertility restoration tool for childhood cancer survivors. However, since in mice, the colonization efficiency of transplanted spermatogonial stem cells (SSCs) is only 12%, the efficiency of the procedure needs to be...

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Bibliographic Details
Main Authors: Prashant Kadam, Elissavet Ntemou, Yoni Baert, Sven Van Laere, Dorien Van Saen, Ellen Goossens
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-1065-0