The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro

The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro

Alzheimer’s disease (AD), the most common neurodegenerative disease, has no effective treatment. Dauricine (DAU), a benzyl tetrahydroisoquinoline alkaloid isolated from the root of Menispermum dauricum DC, reportedly has neuroprotective effects in cerebral ischemia. Here, we investigated the effects...

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Bibliographic Details
Main Authors: Pan Liu, Xiao Chen, Haizhe Zhou, Liqun Wang, Zaijun Zhang, Xiaohu Ren, Feiqi Zhu, Yi Guo, Xinfeng Huang, Jianjun Liu, Peter S. Spencer, Xifei Yang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/2025914

Internet

http://dx.doi.org/10.1155/2018/2025914

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