Circulating zonulin, a marker of intestinal permeability, is increased in association with obesity-associated insulin resistance.

Zonulin is the only physiological mediator known to regulate intestinal permeability reversibly by modulating intercellular tight junctions. To investigate the relationship between intestinal permeability and obesity-associated metabolic disturbances in humans, we aimed to study circulating zonulin...

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Bibliographic Details
Main Authors: José María Moreno-Navarrete, Mònica Sabater, Francisco Ortega, Wifredo Ricart, José Manuel Fernández-Real
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3356365?pdf=render