Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues

Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues

Background: Prenatal alcohol exposure (PAE) can alter the development of neurobiological systems, leading to lasting neuroendocrine, neuroimmune, and neurobehavioral deficits. Although the etiology of this reprogramming remains unknown, emerging evidence suggests DNA methylation as a potential media...

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Bibliographic Details
Main Authors: Alexandre A. Lussier, Tamara S. Bodnar, Matthew Mingay, Alexandre M. Morin, Martin Hirst, Michael S. Kobor, Joanne Weinberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Genetics
Subjects:
prenatal alcohol exposure
fetal alcohol spectrum disorder
brain
development
epigenetics
DNA methylation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00610/full

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