The crosstalk between HIFs and mitochondrial dysfunctions in cancer development
Abstract Mitochondria are essential cellular organelles that are involved in regulating cellular energy, metabolism, survival, and proliferation. To some extent, cancer is a genetic and metabolic disease that is closely associated with mitochondrial dysfunction. Hypoxia-inducible factors (HIFs), whi...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03505-1 |