In Vitro Interaction of AB-FUBINACA with Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes and Drug Transporters

In Vitro Interaction of AB-FUBINACA with Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes and Drug Transporters

AB-FUBINACA, a synthetic indazole carboxamide cannabinoid, has been used worldwide as a new psychoactive substance. Because drug abusers take various drugs concomitantly, it is necessary to explore potential AB-FUBINACA-induced drug–drug interactions caused by modulation of drug-metabolizing enzymes...

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Bibliographic Details
Main Authors: Sunjoo Kim, Dong Kyun Kim, Yongho Shin, Ji-Hyeon Jeon, Im-Sook Song, Hye Suk Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
AB-FUBINACA
drug–drug interaction
cytochrome P450
uridine 5′-diphospho-glucuronosyltransferases
drug transporters
Online Access:https://www.mdpi.com/1420-3049/25/19/4589

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