Astragaloside IV protects cardiomyocytes from hypoxia-induced injury by down-regulation of lncRNA GAS5

Astragaloside IV protects cardiomyocytes from hypoxia-induced injury by down-regulation of lncRNA GAS5

Background: Poor understanding of the regulatory mechanisms of astragaloside IV (AS-IV) in cardiovascular protection limits clinical application of AS-IV in heart failure. Hypoxia is an important stimulus in the progression of heart failure. We investigated the role of AS-IV in hypoxia-treated cardi...

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Bibliographic Details
Main Authors: Jian Du, Jia Liu, Juan Zhen, Si-Tong Yang, En-Lai Zheng, Ji-Yan Leng
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Heart failure
Astragaloside IV
Hypoxia injury
lncRNA GAS5
PI3K/mTOR
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219305347

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http://www.sciencedirect.com/science/article/pii/S0753332219305347

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