Poly‐aneuploid cancer cells promote evolvability, generating lethal cancer
Abstract Cancer cells utilize the forces of natural selection to evolve evolvability allowing a constant supply of heritable variation that permits a cancer species to evolutionary track changing hazards and opportunities. Over time, the dynamic tumor ecosystem is exposed to extreme, catastrophic ch...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-08-01
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Series: | Evolutionary Applications |
Subjects: | |
Online Access: | https://doi.org/10.1111/eva.12929 |