Reciprocal and dynamic polarization of planar cell polarity core components and myosin

The Ciona notochord displays planar cell polarity (PCP), with anterior localization of Prickle (Pk) and Strabismus (Stbm). We report that a myosin is polarized anteriorly in these cells and strongly colocalizes with Stbm. Disruption of the actin/myosin machinery with cytochalasin or blebbistatin dis...

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Bibliographic Details
Main Authors: Erin Newman-Smith, Matthew J Kourakis, Wendy Reeves, Michael Veeman, William C Smith
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/05361