ApoE4 attenuates cortical neuronal activity in young behaving apoE4 rats

ApoE4 attenuates cortical neuronal activity in young behaving apoE4 rats

The E4 allele of apolipoprotein E (apoE4) is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). However, apoE4 may cause innate brain abnormalities before the appearance of AD-related neuropathology. Understanding these primary dysfunctions is vital for the early detecti...

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Bibliographic Details
Main Authors: Ilona Har-Paz, Elor Arieli, Anan Moran
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Neurobiology of Disease
Subjects:
ApoE4
Neuronal activity
Taste learning
Alzheimer's disease
Neuronal information coding
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121001224

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http://www.sciencedirect.com/science/article/pii/S0969996121001224

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