HTS-Driven Discovery of New Chemotypes with West Nile Virus Inhibitory Activity

HTS-Driven Discovery of New Chemotypes with West Nile Virus Inhibitory Activity

West Nile virus (WNV) is a positive sense, single-stranded RNA virus that can cause illness in humans when transmitted via mosquito vectors. Unfortunately, no antivirals or vaccines are currently available, and therefore efficient and safe antivirals are urgently needed. We developed a high throughp...

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Bibliographic Details
Main Authors: Qianjun Li, Shuang Feng, Marintha Heil, E. Lucile White, Subramaniam Ananthan, Blake. P. Moore, Sara N. McKellip, Clinton Maddox, Colleen B. Jonsson, Dong Hoon Chung, Lynn Rasmussen
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Molecules
Subjects:
West Nile virus
high throughput screen
antivirals
chemotypes
Online Access:http://www.mdpi.com/1420-3049/15/3/1690/

Internet

http://www.mdpi.com/1420-3049/15/3/1690/

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