Optimizing the method for generation of integration-free induced pluripotent stem cells from human peripheral blood

Abstract Background Generation of induced pluripotent stem cells (iPSCs) from human peripheral blood provides a convenient and low-invasive way to obtain patient-specific iPSCs. The episomal vector is one of the best approaches for reprogramming somatic cells to pluripotent status because of its sim...

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Bibliographic Details
Main Authors: Haihui Gu, Xia Huang, Jing Xu, Lili Song, Shuping Liu, Xiao-bing Zhang, Weiping Yuan, Yanxin Li
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-0908-z