Equilibrium Thermodynamics, Formation, and Dissociation Kinetics of Trivalent Iron and Gallium Complexes of Triazacyclononane-Triphosphinate (TRAP) Chelators: Unraveling the Foundations of Highly Selective Ga-68 Labeling

Equilibrium Thermodynamics, Formation, and Dissociation Kinetics of Trivalent Iron and Gallium Complexes of Triazacyclononane-Triphosphinate (TRAP) Chelators: Unraveling the Foundations of Highly Selective Ga-68 Labeling

In order to rationalize the influence of FeIII contamination on labeling with the 68Ga eluted from 68Ge/68Ga-generator, a detailed investigation was carried out on the equilibrium properties, formation and dissociation kinetics of GaIII- and FeIII-complexes of 1,4,7-triazacyclononane-1,4,7-tris(meth...

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Bibliographic Details
Main Authors: Adrienn Vágner, Attila Forgács, Ernő Brücher, Imre Tóth, Alessandro Maiocchi, Alexander Wurzer, Hans-Jürgen Wester, Johannes Notni, Zsolt Baranyai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Chemistry
Subjects:
chelates
gallium
iron
thermodynamics
kinetics
reaction mechanism
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00170/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2018.00170/full

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