The Effect of Treadmill Running on Insulin Receptor, Oxidative Stress, and Impaired Synaptic Plasticity in the Brain of High Fat Diet-induced 3xTg-AD Mice

PURPOSE This study investigated the effect of treadmill running on obesity-related brain insulin receptor, oxidative stress, and impaired synaptic plasticity in 3xTg-AD mice (APPSWE, PS1M146V and tauP301L). METHODS At 4 months of age, thirty 3xTg-AD mice were assigned to standard chow (SC, n=10) or...

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Bibliographic Details
Main Author: Dong-Hyun Kim
Format: Article
Language:Korean
Published: The Korean Society of Exercise Physiology 2018-08-01
Series:운동과학
Subjects:
Online Access:http://www.ksep-es.org/upload/pdf/es-27-3-191.pdf