DoGNet: A deep architecture for synapse detection in multiplexed fluorescence images.

Neuronal synapses transmit electrochemical signals between cells through the coordinated action of presynaptic vesicles, ion channels, scaffolding and adapter proteins, and membrane receptors. In situ structural characterization of numerous synaptic proteins simultaneously through multiplexed imagin...

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Bibliographic Details
Main Authors: Victor Kulikov, Syuan-Ming Guo, Matthew Stone, Allen Goodman, Anne Carpenter, Mark Bathe, Victor Lempitsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007012