The effect of adenosine A2A receptor antagonist istradefylline on multiple organ dysfunction in heatstroke rats

The effect of adenosine A2A receptor antagonist istradefylline on multiple organ dysfunction in heatstroke rats

Background: Global warming increases the incidence of heatstroke, which is the most severe heat illness. The mortality in patients with heatstroke is due to neurological disability and multiple organ failure caused by systemic inflammatory response. Adenosine A2A receptor antagonist has both neuropr...

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Bibliographic Details
Main Authors: Chih-Chin Shih, Jye-Hann Chen, Mei-Hui Liao, Cheng-Ming Tsao, Hsieh-Chou Huang, Chin-Chen Wu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Journal of Medical Sciences
Subjects:
heatstroke
a2a receptor
istradefylline
multiple organ dysfunction
Online Access:http://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2020;volume=40;issue=2;spage=76;epage=82;aulast=Shih

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http://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2020;volume=40;issue=2;spage=76;epage=82;aulast=Shih

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