Blunted sodium excretion in response to a saline load in 5 year old female sheep following fetal uninephrectomy.

Previously, we have shown that fetal uninephrectomy (uni-x) causes hypertension in female sheep by 2 years of age. Whilst the hypertension was not exacerbated by 5 years of age, these uni-x sheep had greater reductions in renal blood flow (RBF). To further explore these early indications of a declin...

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Bibliographic Details
Main Authors: Yugeesh R Lankadeva, Reetu R Singh, Lucinda M Hilliard, Karen M Moritz, Kate M Denton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471853?pdf=render