Dimerization of cell-penetrating buforin II enhances antimicrobial properties

Abstract Antimicrobial peptides (AMPs) that selectively permeabilize bacterial membranes are promising alternatives to conventional antibiotics. Dimerization of AMP is considered an attractive strategy to enhance antimicrobial and membrane-lytic activity, but it also increases undesired hemolytic an...

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Bibliographic Details
Main Authors: Hyunhee Lee, Sungtae Yang
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:Journal of Analytical Science and Technology
Subjects:
Online Access:https://doi.org/10.1186/s40543-021-00264-8